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Adults—At first, 10 milligrams (mg) once a day. Fetal Toxicity fetal/neonatal morbidity/mortality may occur when drugs that act directly on the renin-angiotensin system are used in pregnancy; D/C drug ASAP once pregnancy detected Adult Dosing . Lisinopril is also used to treat congestive heart failure in adults, or to improve survival after a heart attack. Lisinopril is used to treat hypertension (high blood pressure) and heart failure . As a result, lisinopril relaxes the blood vessels. Prices are for specific doses and days supplies of the drug; prices may vary for different doses and day supplies. Lisinopril is a white to off-white, crystalline powder, with a molecular weight of 441. Lisinopril may also be used for purposes not listed in this medication guide. Lisinopril oral tablet is used to treat hypertension (high blood pressure) and heart failure. When prescribed for heart failure with a . Children—Dose is based on body weight and must be determined by your doctor. 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